leptin相关论文
目前患肥胖且伴有糖尿病的人数日益增多,临床用于治疗肥胖糖尿病的有效方式大多通过药物和手术治疗,但往往会产生较大的副作用。如......
目的 探讨Leptin对体外培养的缺氧状态下视网膜祖细胞(RPCs)增殖、分化的影响及细胞中PTEN蛋白表达的变化.方法 原代培养大鼠RPCs,......
为了研究瘦素（Leptin）对大鼠乳腺发育的调节作用,本文以处女期、妊娠溯和泌乳期SD大鼠的乳腺组织为研究对象,用RT-PCR法、放射免疫法......
目的:探讨干扰小RNA(siRNA)下调瘦素(leptin)的表达对体外培养的人病理性瘢痕成纤维细胞增殖能力及转化生长因子-βn 1(TGF-......
第一部分Leptin对内皮细胞的氧化应激以及增殖的影响目的:观察Leptin对脐静脉内皮细胞（HUVECs）的氧化应激作用及增殖的影响。方法:（1）......
目的 探讨乳腺癌临床病理特征和临床预后与血清Leptin、蛋白激酶Cε(PKCε)的相关性.方法 选取河北大学附属医院2017年11月至2018......
肥胖及代谢综合征（metabolic syndrome,MetS）近年来已成为严重危害人类健康及生命的重大疾病。为了深入研究该疾病的发生机制、筛选......
目的:一、研究大鼠脊髓损伤合并股骨骨折时外周血清leptin水平及骨痂组织中Leptin的表达,探讨Leptin在骨折愈合过程中的所起的作用......
第一部分腰椎黄韧带细胞的体外分离、培养、扩增及表型鉴定目的建立黄韧带细胞体外分离、培养、扩增及表型鉴定的方法,为后续黄韧......
炎症性肠病（inflammatory bowel disease，IBD）是一种病因和发病机制尚未完全阐明的慢性复发性肠道炎性反应性疾病，由于其病程迁延不愈......
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Accumulating evidence suggests that obesity is associated with chronic pain.However,whether obesity is associated with a......
Aim: To investigate the in vitro effects of insulin and leptin on human sperm motility, viability, acrosome reaction and......
Aim: To evaluate the expression of leptin and leptin receptor in benign prostatic hyperplasia (BPH) and prostate cancer ......
This study examined the effects of melatonin on leptin?induced changes in sperm parameters in adult rats. Five groups of......
Leptin,an adipocyte-derived hormone,serves numerous physiological functions in the body,particularly during puberty and ......
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Decreased accumulation of ultrasound contrast in the liver of nonalcoholic steatohepatitis rat model
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Expression of steroidogenic enzymes and leptin receptor in the testes of wild male Ground Squirrel(C
To adapt to the environment and ensure their offspring survive,wildlife formed their own unique reproductive strategies ......
Expression of PCNA,c-kit receptor,PPARγ2,leptin and leptin receptor in the oviduct of Rana dybowskii
Rana dybowskii is a special amphibian in northeastern China,as it has been used widely in traditional Chinese medicine.R......
Leptin regulated the expression of cytokines involved in embryo implantation in primary porcine endo
There is increasing evidence that leptin may be directly involved in mammalian reproduction.In our previous study,the ob......
1994年底zhang等利用定位克隆技术克隆出了肥胖基因(obese gene,ob基因),并通过定性研究表明ob基因的蛋白产物leptin具有抑制摄食......
Environmental cues,as temperature and photoperiod,play an important role in the seasonal regulation of an animals physio......
为了观察产复康对产后气虚血瘀证奶牛Leptin和产后1～4周产奶量的变化,将58头产后奶牛分为气虚血瘀证组和临床健康组,并进一步将这两......
Accumulating evidence suggests that microRNAs(miRNAs)play an important role in regulating the pathways in adipose tissue......
光照持续时间,强度和光质量对家鸡生长和繁殖活动均有影响.本试验研究光周期对地方蛋鸡—芦花鸡的体重,血浆激素浓度,开产性能,产......
Seasonal changes of thermogenic properties in Yunnan red-backed vole (Eothenomys miletus) from Hengd
Environmental cues, including photoperiod and temperature, play important roles in the adjusting of an animals physiolog......
Hengduan Mountains region, located at the boundary between the Palearctic region and the Oriental region is an alp and g......
In vitro effect of β-hydroxybutyric acid, leptin and insulin on leptin and its receptor mRNA express
Leptin is an adipocyte-derived hormone/cytokine that links nutritional status and hypothesized to function as a negative......
Leptin Regulated the Expression of Cytokines Involving in Embryo Implantation in Primary Porcine End
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本研究试图查明南宁地区某规模化奶牛场荷斯坦奶牛分娩前后血浆中Leptin、酮体、葡萄糖、脂肪的水平及其各自动态变化的特点,揭示L......
Negative energy balance (NEB),which is characterized by low serum glucose and hyperketonemia,is the pathology basis of k......
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目的：观察脊髓损伤(SCI)合并骨折的动物模型体内血清以及骨痂中leptin的表达变化与骨折愈合的关系。方法：72只雄性SD大鼠随机分成4组......
SerumLeptin,BoneMineralDensityandfracturehealinginlongboneFracturedMenWithSpinalCord
Previous reported rates of fractures in spinal cord injury(SCI)patients range from 1%to 20%.The understanding of the exa......
Relationship between serum leptin levels and bone mineral density in obese children:a systematic rev
Obesity causes larger bone size and bone mass,but the association between leptin and bone mineral density is notelucidat......
Role of the local bone,fat and nerve endocrine function in steroidinduced osteonecrosis in a rat mod
Background: Osteonecrosis of the femoral head(ONFH)is a severe complication of glucocorticoid treatment.The precise mech......
Aim: To explore the mechanism of suppressive effects of 3-daidzein sulfonate (DSS) on obesity in ovariectomized (Ovx) ra......
LeptinhasbeensuggestedtoplayaroleintheetiologyofAdolescentIdiopathicScoliosis(AIS),however,theleptinlevelsinAISgirlsares......
Effects of stimulation of medial amygdala on food intake of the rat and the possible mechanisms invo
Lesions of the amygdala have long been known to produce hyperphagia and obeisty in cats,dogs and monkeys.However,there w......
Objective: To observe the effect of leptin on matrix metalloproteinases-9 and inflammatory Cytokines Expression in ather......
Hydrogen sulfide antagonizes Formaldehyde-induced neurotoxicity by inhibition of autophagy via upreg
Formaldehyde (FA) has neurotoxicity and we have previously demonstrated that hydrogen sulfide (H2S),the third gasotransm......
Leptin Attenuates Contractile Function in Adult Rat Cardiomyocytes Involved Oxidative Stress and Aut
Aim Leptin, a 16 ku hormone from the ob gene, has been identified as an important protein involved obesity.As a chronic ......
We aim to investigate the changes in expression levels of metabolite and appetite control factors caused by different di......
